Passive skill tree / keystone

Chaos Inoculation

Chaos Inoculation is a keystone on the Path of Exile 2 passive skill tree.

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Effect

1 line

Maximum Life is 1 Immune to Chaos Damage and Bleeding

Give up everything in pursuit of greatness - even life itself.

Related mechanics

MechanicBleeding

Bleeding is a damaging Ailment that deals Physical damage over time and bypasses Energy Shield. It lasts five seconds by default and requires an explicit chance or effect that can inflict Bleeding.

Direct tree connections

small / direct edgeAttribute+5 to any Attribute

Nearby major passives

notable / 4 edgesHeavy Frost20% increased Freeze Buildup notable / 4 edgesShimmering MirageGain additional Ailment Threshold equal to 30% of maximum Energy Shield notable / 4 edgesAbasement20% increased Stun Recovery notable / 4 edgesThin Ice20% increased Freeze Buildup notable / 4 edgesControlled ChaosMaximum Volatility is 30 keystone / 4 edgesConduitIf you would gain a Charge, Allies in your Presence gain that Charge instead notable / 5 edgesBrain Freeze20% increased Cold Damage notable / 5 edgesCareful Assassin20% reduced Critical Damage Bonus notable / 5 edgesInvocated Efficiency10% increased Mana Cost Efficiency notable / 6 edgesTurn the Clock Forward20% increased Spell Damage notable / 6 edgesEchoing PulseEchoed Spells have 25% increased Area of Effect notable / 6 edgesMending Deflection15% of Damage taken from Deflected Hits Recouped as Life notable / 6 edgesMental Alacrity5% increased Cast Speed notable / 6 edgesHarsh Winter8% increased Cast Speed with Cold Skills notable / 6 edgesBone ChainsPhysical Spell Critical Hits build Pin notable / 6 edgesEffervescent4% increased Cast Speed for each different Spell you've Cast in the last eight seconds notable / 6 edgesHaemorrhaging CutsEnemies you inflict Bleeding on cannot Regenerate Life notable / 6 edgesTurn the Clock Back15% increased Spell Damage notable / 6 edgesEnergise25% chance for Trigger skills to refund half of Energy Spent notable / 6 edgesWither AwayUnwithered enemies are Withered for 8 seconds when they enter your Presence notable / 6 edgesLucidity8% of Damage is taken from Mana before Life notable / 6 edgesFated End30% increased Curse Duration notable / 7 edgesRemnant Attraction10% chance to create an additional Remnant notable / 7 edgesTempered Mind15% increased effect of Fully Broken Armour notable / 7 edgesConvalescence10% reduced Energy Shield Recharge Rate notable / 7 edgesInvigorating ArchonArchon Buffs also grant +20% to all Elemental Resistances notable / 7 edgesEnergising Archon30% increased Archon Buff duration notable / 7 edgesBrain Storm20% increased Lightning Damage notable / 7 edgesThe Soul MeridianGain Deflection Rating equal to 8% of Evasion Rating notable / 7 edgesPure ChaosGain 11% of Damage as Extra Chaos Damage